Yes you can do either or, 108 Vibrations work for everything. Whichever Rune you use you can use Multiples of its number as you said. As with Sanskrit mantras use x108 and if the energy is too much you can go to x54 Raum you can do x40
I myself am about to Start Algiz x108 to clean my aura x11 times into each chakra and x31 into my aura
Do what you are most comfortable with, everyone is different. Also always make sure sure you watch out for VOID of COURSE The Void of Course Moon Lunarium: Universal Lunar Calendar you can set your location and use this calendar to figure out when the Void of Course moon will be in your area.
-Don't ever let anyone stop you NOT even your own SELF
