Other #77515 Handicapped/Down Syndrome, etc. ?

[Ask Satya Operator]

Question: Why are some born handicapped, crippled, missing a limb, or have Down Syndrome? I know now I have to be careful who I listen to regarding soul, life, and reincarnation. Nevertheless, I was once informed that it's due to heavy karma, especially if you are born with Down Syndrome, which is due to having committed suicide. The sould starts all over again, but with degradation when coming back into physical life. The religious Christian claims it's a curse to the parents because "God" blesses and curses.
What is your take on the topic? And if some of it is true, is the a chance for a change into other incarnations?
Links are appreciated if there's readings regarding the topic