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As a bad exampel, if someone would do 900 days a binding spell Isa Rune 108 reps on a person. What would happen with this person?
Normaly as you did mention 40 or 90 are enouth for a lifetime. considering everything was done right (affirmation,... etc).
What happens if someone does a working to long? (besides wasting energy,time)
I gess for white magic there are no other bad effects.
Now first off, I did not say that 40 or 90 days would be enough for a lifetime. This is not the case most of the time. Most workings are not a "one shot deal". There is a page on the ToZ about this.
What I said is cycles of 40 or 90 days. So you do one "cycle" of 40 days, for example, and then a few days/weeks later on a fitting date, you do another cycle of the same working. And so on until you attain the desired result, or until you can strongly feel that enough energies have been put into motion towards it. That's the basic concept of doing cycles, atleast in the way I understand it.
Now for your example here. I think that something like this would be bad in a variety of ways. In this specific case it is because of the rune in question. Isa has icy and stagnative qualities. It stops things and slows them down. And in the end, even if you vibrate a rune into someone else, as with the binding spell, you still have that rune's energy inside of yourself, too. This is the reason why we cannot currently use "death mantras" in black magick. Because the energy would stick to our soul and ruin us.
So in this example you would not only overload the target with Isa energies, causing them many mental and perhaps even physical issues (in addition to successfully binding them of course), but you would also overload yourself with Isa energies, causing you similar issues. Perhaps the Isa rune here was a bit of a bad example because it has harmful qualies when overused.
To give a different example, say you use the mantra zAsitR on someone for a binding spell instead. It goes for the opposite approach of Isa, instead of stagnating and "freezing" the target, he/she is dominated by you instead, in such a way that he/she submits to you and follows your desires. In this case, doing a working for 900 days would not be harmful at all. As long as the affirmations are properly worded, nothing bad will happen to the target unless you desire it, so all that happens is that your control over the target is even further emphasized to the point where there is no resistance even if you gave orders to do something that the target is completely adverse to (for example, telling the target to do something they hate, or are extremely scared of).
And in regards to yourself, the mantra would only increase dominative qualities in you, e.g. it would "passively" increase your ability to command and order others with authority.