You can but that's not advisable. If you remove beneficial Saturn karma, you'll basically fuck your life up. No consistency, no structure, no organisation, no staying power, no understanding of hierarchy and separation. If you remove these, you'll never achieve anything in life. You'll become ignorant and decay.
As for removing harmful Saturn karma, HPS Lydia has made a post a long time ago. It's called something like "Obliterate your Saturn". Look it up.